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((2S,3S)-4-(Anthracen-9-Yl)-3-(tert-Butyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Di-tert-Butylphosphine Oxide CAS NO 2374143-29-8


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CAS No.:2374143-29-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

((2S,3S)-4-(Anthracen-9-Yl)-3-(tert-Butyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Di-tert-Butylphosphine Oxide is a sophisticated, chiral organophosphorus compound featuring a unique fused oxaphosphole ring system. This compound is of significant value as a specialized ligand or catalyst precursor in advanced synthetic chemistry, particularly for asymmetric transformations. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and high-value intermediates.

Application

This high-purity chiral phosphine oxide is engineered for precision applications in synthetic chemistry and materials science.

  • Asymmetric Catalysis: Serving as a precursor for chiral phosphine ligands used in metal-catalyzed cross-coupling, hydrogenation, and hydroformylation reactions.
  • Pharmaceutical Intermediate Synthesis: A key building block in the multi-step synthesis of complex, stereochemically defined drug candidates.
  • Advanced Material Research: Exploration of its use in the development of chiral organic electronic materials or as a component in molecular recognition systems.
  • Methodology Development: Utilized by academic and industrial research groups to develop new catalytic protocols and synthetic methodologies.
  • Process Chemistry: Evaluation for scale-up in the production of enantiomerically pure fine chemicals.

Basic Information

Product Name ((2S,3S)-4-(Anthracen-9-Yl)-3-(tert-Butyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Di-tert-Butylphosphine Oxide
CAS No. 2374143-29-8
Molecular Formula C35H42O2P2
Molecular Weight 556.64 g/mol
Synonyms Di-tert-butyl((2S,3S)-4-(anthracen-9-yl)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl)phosphine oxide; (2S,3S)-4-(Anthracen-9-yl)-3-(tert-butyl)-2,3-dihydrobenzo[d][1,3]oxaphosphol-2-yl di-tert-butylphosphine oxide; Chiral Oxaphosphole Phosphine Oxide; Anthracene-fused Chiral Phosphine Oxide Ligand Precursor
EINECS Contact for details

Quality Control

Our production of this advanced chiral chemical adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from physical damage.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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