Description

(3Ar,3A'R,7Ar,7A'R)-2,2'-(((2S,4S)-Pentane-2,4-Diyl)Bis(Oxy))Bis(1,3-Diphenyloctahydro-1H-Benzo[D][1,3,2]Diazaphosphole) is a sophisticated chiral organophosphorus compound, specifically designed as a high-performance ligand for asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals with superior purity and efficacy. This product is essential for research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise stereochemical control in their synthetic processes.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, such as hydrogenation, hydrosilylation, and cross-coupling.
• For the enantioselective synthesis of pharmaceutical intermediates and active ingredients.
• In the development and scale-up of proprietary catalytic processes for fine chemical production.
• As a key component in catalyst screening kits for high-throughput experimentation in R&D laboratories.
• For the synthesis of agrochemicals requiring specific stereochemistry for optimal biological activity.
• In academic and industrial research focused on advancing organocatalysis and novel catalytic methodologies.

Basic Information

Product Name	(3Ar,3A'R,7Ar,7A'R)-2,2'-(((2S,4S)-Pentane-2,4-Diyl)Bis(Oxy))Bis(1,3-Diphenyloctahydro-1H-Benzo[D][1,3,2]Diazaphosphole)
CAS No.	2370958-37-3
Molecular Formula	C45H52N4O2P2
Molecular Weight	742.87 g/mol
Synonyms	Chiral Diazaphosphole Ligand; (S,S)-DIPHOS-DABN Derivative; Asymmetric Catalyst Ligand 2370958-37-3; 1,3-Diphenyloctahydro-1H-benzo[d][1,3,2]diazaphosphole-based ligand; BINOL-Derived Phosphoramidite Analog; (2S,4S)-Pentane-2,4-diyl bis(1,3-diphenyloctahydro-1H-benzo[d][1,3,2]diazaphosphole-2-oxide) (tautomer); P,P'-Bidentate Ligand
EINECS	Contact for details

Quality Control

Our production of this high-value chiral ligand adheres to strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Quality is verified through comprehensive analytical techniques including HPLC for chiral purity and assay, NMR for structural confirmation, and elemental analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and enantiomeric excess is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when dispensing to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.