Description

Benzenebutanoic Acid, 4-(Acetylamino)-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- is a specialized, high-purity chemical building block designed for advanced research and pharmaceutical development. This compound is critical for the synthesis of complex peptides and other bioactive molecules, offering researchers precise control over molecular structure. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in drug discovery and proteomics.

Application

• Pharmaceutical Intermediate: Serves as a key protected amino acid derivative in the solid-phase peptide synthesis (SPPS) of novel therapeutic peptides.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Proteomics Research: Employed as a tool compound for studying protein-protein interactions and enzyme mechanisms.
• Combinatorial Chemistry: A valuable building block for creating diverse chemical libraries for high-throughput screening.
• Biomarker Development: Can be incorporated into probes and tags for diagnostic assay development.
• Academic Research: Used in graduate-level and post-doctoral research focused on synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	Benzenebutanoic Acid, 4-(Acetylamino)-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)-
CAS No.	2349593-63-9
Molecular Formula	C27H26N2O5
Molecular Weight	458.51 g/mol
Synonyms	Fmoc-4-Acetamidophenylalanine; Fmoc-Phe(4-AcNH)-OH; N-α-Fmoc-N-γ-acetyl-4-aminophenylalanine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetamidophenyl)propanoic acid; 4-Acetamido-L-phenylalanine, N-α-Fmoc derivative; Fmoc-4-AcNH-Phe-OH; N-α-(9-Fluorenylmethoxycarbonyl)-N-γ-acetyl-4-aminophenylalanine; Protected 4-Acetamidophenylalanine
EINECS	Contact for details

Quality Control

Our production of Benzenebutanoic Acid, 4-(Acetylamino)-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (αs)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.