Description

1H-Indene-2-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2,3-Dihydro-, (αs)- is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic syntheses. It is primarily utilized in the pharmaceutical and advanced materials sectors for the development of novel active pharmaceutical ingredients (APIs) and sophisticated organic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for complex, chiral molecules.
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) as a protected amino acid derivative, facilitating the controlled assembly of peptide chains.
• Organic Synthesis Research: Serves as a versatile intermediate in academic and industrial R&D for constructing complex heterocyclic and polycyclic compounds.
• Protecting Group Strategy: The 9-Fluorenylmethoxycarbonyl (Fmoc) group is a cornerstone for amine protection in multi-functional molecule synthesis.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, ligands for catalysts, or specialty polymers with tailored properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1H-Indene-2-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2,3-Dihydro-, (αs)-
CAS No.	2349462-94-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2,3-dihydro-1H-indene-2-propanoic acid; Fmoc-(S)-2,3-dihydro-1H-indene-2-propanoic acid; Fmoc-Dip-2-OH; Fmoc-2,3-dihydro-1H-indene-2-yl-Ala-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3-dihydro-1H-inden-2-yl)propanoic acid; Protected (S)-2-amino-3-(2,3-dihydro-1H-inden-2-yl)propanoic acid; Fmoc-Dip(2-OH)-OH; Fmoc-2-Indanylglycine derivative
EINECS	Contact for details

Quality Control

Our 1H-Indene-2-Propanoic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.