Description

Palbociclib-006 is a high-purity chemical intermediate and reference standard, identified by CAS No. 2340184-77-0. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the field of oncology. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories engaged in the development of targeted cancer therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and related active pharmaceutical ingredients (APIs).
• Research & Development: Serves as a crucial reference standard and starting material for medicinal chemistry and drug discovery programs.
• Oncology Drug Development: Used in the R&D of targeted cancer therapeutics, specifically in pathways involving cyclin-dependent kinases (CDKs).
• Analytical Standard: Provides a high-purity benchmark for method development, validation, and quality control testing in analytical laboratories.
• Process Chemistry: Employed in scale-up studies and process optimization for the commercial manufacturing of advanced pharmaceutical compounds.

Basic Information

Product Name	Palbociclib-006
CAS No.	2340184-77-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity; Palbociclib Related Compound; CDK4/6 Inhibitor Intermediate; IBRANCE Impurity; PD-0332991 Intermediate
EINECS	Contact for details

Quality Control

Our Palbociclib-006 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.