Description

Benzonitrile, 4-[3-[2-(4-Hydroxy-1-Piperidinyl)Acetyl]-2,5-Dimethyl-1H-Pyrrol-1-Yl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), where precise molecular architecture is paramount. Pharmaceutical R&D and process chemistry teams need this material for developing next-generation therapeutic agents, particularly in targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, especially for central nervous system (CNS) and receptor-targeted therapies.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct sophisticated nitrogen-containing heterocycles common in modern medicinal chemistry.
• Research & Development (R&D): Essential for academic and industrial research laboratories exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable synthetic pathways from milligram to kilogram scale for clinical trial material production.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations engaged in the custom synthesis of APIs for pharmaceutical clients.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Item	Detail
Product Name	Benzonitrile, 4-[3-[2-(4-Hydroxy-1-Piperidinyl)Acetyl]-2,5-Dimethyl-1H-Pyrrol-1-Yl]-
CAS No.	2307472-03-1
Molecular Formula	C20H25N3O2
Molecular Weight	339.44 g/mol
Synonyms	4-[3-[2-(4-Hydroxypiperidin-1-yl)acetyl]-2,5-dimethyl-1H-pyrrol-1-yl]benzonitrile; 1-(4-Cyanophenyl)-2,5-dimethyl-3-[2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-1H-pyrrole; 4-(3-(2-(4-Hydroxypiperidin-1-yl)-2-oxoethyl)-2,5-dimethyl-1H-pyrrol-1-yl)benzonitrile; (4-Hydroxy-1-piperidinyl)-[1-(4-cyanophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methanone; Advanced Pyrrole-Piperidine Pharmaceutical Intermediate
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-[3-[2-(4-Hydroxy-1-Piperidinyl)Acetyl]-2,5-Dimethyl-1H-Pyrrol-1-Yl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, supporting regulatory filings for investigational new drugs (IND).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.