Description

2-Chloro-4-Fluoro-3-Methylphenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in the development of small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, enabling the introduction of specific halogenated aromatic structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and molecular components for OLEDs and sensors.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-Chloro-4-Fluoro-3-Methylphenylboronic Acid
CAS No.	2304633-76-7
Molecular Formula	C7H7BClFO2
Molecular Weight	187.39 g/mol
Synonyms	(2-Chloro-4-fluoro-3-methylphenyl)boronic acid; 2-Chloro-4-fluoro-3-methylbenzeneboronic acid; B-(2-Chloro-4-fluoro-3-methylphenyl)boronic acid; 2304633-76-7; Boronic acid, B-(2-chloro-4-fluoro-3-methylphenyl)-; 2-Chloro-4-fluoro-3-methylphenylboronic acid pinacol ester (related ester)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.