Description

1-Cyclopropyl-4-Ethynyl-1H-Pyrazole is a high-purity, functionalized pyrazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block, enabling the construction of complex molecular architectures through its reactive ethynyl and pyrazole moieties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Acts as a starting material for creating specialized ligands in catalysis and coordination chemistry.
• Material Science: Employed in the research and development of advanced organic electronic materials and polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The ethynyl group makes it an excellent substrate for Sonogashira and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	1-Cyclopropyl-4-Ethynyl-1H-Pyrazole
CAS No.	2297839-58-6
Molecular Formula	C8H8N2
Molecular Weight	132.16 g/mol
Synonyms	4-Ethynyl-1-cyclopropyl-1H-pyrazole; 1H-Pyrazole, 1-cyclopropyl-4-ethynyl-; 1-Cyclopropyl-4-ethynylpyrazole; 4-Ethynyl-1-cyclopropylpyrazole
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-4-Ethynyl-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and should be handled with care to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.