Description

Ph-Low Insertion Peptide CAS NO 2293160-09-3 is a specialized synthetic peptide designed for targeted biochemical research and therapeutic development. This compound is engineered for precise interaction with low pH environments, making it a critical tool for studying cellular mechanisms and drug delivery systems. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, diagnostics, and advanced therapeutic modalities.

Application

• Targeted Drug Delivery Systems: As a key component in the design of pH-sensitive carriers for chemotherapeutic agents.
• Cancer Research: For studying tumor microenvironment targeting and the mechanisms of selective cellular uptake in acidic conditions.
• Diagnostic Probe Development: In the creation of imaging agents and biosensors that activate in specific pH ranges.
• Peptide Therapeutics: Serving as a structural motif or conjugate in the development of novel peptide-based pharmaceuticals.
• Bioconjugation & Labeling: For attaching payloads (e.g., fluorophores, toxins) to molecules intended for acidic target sites.
• Academic & Mechanistic Studies: Investigating membrane interactions, endosomal escape, and other pH-dependent biological processes.

Basic Information

Product Name	Ph-Low Insertion Peptide
CAS No.	2293160-09-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	pH-Low Insertion Peptide; pHLIP Peptide; Acidic pH Insertion Peptide; Tumor-targeting pH-sensitive peptide; pH-triggered membrane peptide; CAS 2293160-09-3; Low pH Insertion Sequence
EINECS	Contact for details

Quality Control

Our Ph-Low Insertion Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.