Description

Biotin-Peg11-Ch2Ch2N3 is a high-purity, heterobifunctional polyethylene glycol (PEG) linker designed for advanced bioconjugation and click chemistry applications. This compound is engineered to facilitate the precise attachment of biotinylated molecules to azide-functionalized targets, enabling robust and site-specific labeling in complex biological systems. It is an essential reagent for researchers and developers in the fields of pharmaceutical R&D, proteomics, diagnostic assay development, and advanced material science, where controlled biomolecule assembly is critical.

Application

• ADC (Antibody-Drug Conjugate) Development: As a key linker component for constructing stable, cleavable bioconjugates with controlled drug-to-antibody ratios (DAR).
• Diagnostic Probe Synthesis: For creating sensitive detection probes by linking biotinylated antibodies or oligonucleotides to azide-modified surfaces or reporter molecules.
• Biomaterial Functionalization: To introduce biotin groups onto azide-presenting polymers, hydrogels, or nanoparticles for subsequent streptavidin-based assembly.
• Protein and Cell Labeling: Enables site-specific tagging of azide-modified proteins or glycans with biotin for purification, pull-down assays, or imaging via streptavidin conjugates.
• Click Chemistry Toolkits: Serves as a critical reagent in research kits for copper-free click chemistry applications, offering improved biocompatibility.
• Drug Delivery System Engineering: Used to fabricate targeted delivery platforms by conjugating targeting ligands (via biotin-streptavidin) to azide-functionalized carriers.

Basic Information

Product Name	Biotin-Peg11-Ch2Ch2N3
CAS No.	2276672-04-7
Molecular Formula	C58H104N6O18S
Molecular Weight	1205.5 g/mol
Synonyms	Biotin-PEG11-azide; Biotin-PEG11-N3; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl)pentanamide; Biotinylated PEG Azide; Biotin-PEG11-CH2CH2N3; Azido-PEG11-Biotin; N3-PEG11-Biotin
EINECS	Contact for details

Quality Control

Every batch of Biotin-Peg11-Ch2Ch2N3 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We guarantee high batch-to-batch consistency and purity suitable for sensitive research and development applications. A detailed Certificate of Analysis (COA) providing results for identity, purity, and functional integrity is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C. Under these conditions, the product is stable for at least 24 months. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Integrity (NMR/Click Assay)	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.