Description

16:0 Dbco Pe is a high-purity, functionalized lipid derivative designed for advanced bioconjugation and materials science applications. This compound is critical for researchers and manufacturers requiring precise, copper-free click chemistry for labeling, surface modification, and the development of lipid-based delivery systems. It is primarily utilized by professionals in pharmaceutical R&D, biotechnology, and advanced material synthesis who demand reliable, high-quality building blocks for their innovative projects.

Application

• Bioconjugation Reagent: Used for copper-free, strain-promoted azide-alkyne cycloaddition (SPAAC) to label biomolecules like antibodies, proteins, and oligonucleotides.
• Lipid Nanoparticle (LNP) Formulation: Serves as a functional component for modifying lipid nanoparticles, enhancing targeting or stability for drug and gene delivery applications.
• Surface Functionalization: Enables the covalent attachment of biomolecules or polymers to surfaces for biosensor development, microarray fabrication, and cell culture substrates.
• Polymer Chemistry: Acts as a reactive monomer or cross-linker for synthesizing functional polymers and hydrogels with tailored biological properties.
• Diagnostic Probe Development: Facilitates the creation of fluorescent or other labeled probes for in vitro and in vivo imaging and detection.
• Chemical Biology Research: A key tool for studying lipid-protein interactions, membrane dynamics, and cellular trafficking pathways.

Basic Information

Product Name	16:0 Dbco Pe
CAS No.	2260670-42-4
Molecular Formula	C41H68N2O5
Molecular Weight	668.99 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyne; DPPE-DBCO; DBCO-PE(16:0); Dibenzocyclooctyl-PE; DBCO® Phosphatidylethanolamine (16:0); N-(Dibenzocyclooctyn-4-yloxycarbonyl)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine; DBCO-PEG-PE; (16:0) DBCO PE Lipid
EINECS	Contact for details

Quality Control

Every batch of 16:0 Dbco Pe is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and performance. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with the standards expected for research-grade and GMP-starting materials used in critical life science applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, DMSO, DMF
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.