Description

Potassium n-Boc Cyclobutylmethyl Borate is a high-value organoboron reagent featuring a protected amine group. This compound is critical for modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials research organizations for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing cyclobutyl or protected amine motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for palladium-catalyzed carbon-carbon bond formation, essential for constructing biaryl and complex aromatic structures.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific steric and electronic properties.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where precise molecular architecture is required.
• Peptide Mimetics & PROTACs: Facilitates the introduction of the cyclobutylmethyl group into peptide backbones or linker systems for proteolysis-targeting chimeras.
• Chemical Biology Probes: Used to create tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	Potassium n-Boc Cyclobutylmethyl Borate
CAS No.	2254447-10-2
Molecular Formula	C10H18BKO4
Molecular Weight	252.16 g/mol
Synonyms	Potassium (tert-Butoxycarbonylaminomethyl)cyclobutylborate; Potassium Boc-Cyclobutylmethylboronate; Cyclobutylmethylboronic acid N-Boc-protected potassium salt; Potassium [(tert-Butoxycarbonylamino)methyl]cyclobutylborate; (N-Boc-Aminomethyl)cyclobutylboronic Acid Potassium Salt; Potassium Cyclobutylmethyl-Boc-Aminomethylboronate; Potassium (N-Boc-aminomethyl)cyclobutylboronate
EINECS	Contact for details

Quality Control

Our Potassium n-Boc Cyclobutylmethyl Borate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its hygroscopic nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.