Description

Deferasirox Impurity 6 is a specified impurity of the iron-chelating pharmaceutical agent Deferasirox. This compound is critical for analytical method development, stability studies, and ensuring the quality and safety of the active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers, analytical laboratories, and regulatory bodies for research, quality control, and compliance purposes.

Application

• As a reference standard for the identification and quantification of impurities in Deferasirox API and finished drug products.
• For analytical method development and validation (HPLC, LC-MS) in pharmaceutical quality control laboratories.
• In stability studies and forced degradation studies to monitor impurity profiles.
• For regulatory compliance and filing (e.g., ICH guidelines) requiring impurity characterization.
• Used in research and development to understand the degradation pathways of Deferasirox.
• As a critical material for calibrating laboratory equipment used in pharmaceutical analysis.

Basic Information

Product Name	Deferasirox Impurity 6
CAS No.	2254105-61-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Deferasirox Related Compound 6; Deferasirox EP Impurity G; Deferasirox USP Impurity; 4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid impurity; ICL670 Impurity 6; EXJADE Impurity 6; JADENU Impurity 6; Deferasirox Degradant
EINECS	Contact for details

Quality Control

Our Deferasirox Impurity 6 is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical reference standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from HPLC, NMR, and MS analyses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time matches reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Single unspecified impurity ≤ 1.0% Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.