Description

S(R)]-n-[(1S)-1-[2-(Dicyclohexylphosphino)Phenyl]-2,2-Dimethylpropyl]-N,2-Dimethyl-2-Propanesulfinamide is a high-value, chiral sulfinamide-phosphine hybrid ligand, a critical component in asymmetric catalysis. Its precise stereochemistry and unique electronic properties make it indispensable for constructing complex chiral centers with high enantioselectivity and yield. This advanced ligand is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and other high-value specialty chemicals.

Application

• As a chiral ligand in asymmetric transition-metal catalysis, particularly for cross-coupling reactions.
• Enabling enantioselective synthesis of pharmaceutical intermediates and active ingredients (APIs).
• Facilitating asymmetric hydrogenation and C-H activation reactions in fine chemical production.
• Used in academic and industrial research for developing novel catalytic methodologies.
• Critical for the production of optically pure compounds in the agrochemical and fragrance industries.
• Employed in the synthesis of complex natural products and other structurally demanding molecules.

Basic Information

Product Name	S(R)]-n-[(1S)-1-[2-(Dicyclohexylphosphino)Phenyl]-2,2-Dimethylpropyl]-N,2-Dimethyl-2-Propanesulfinamide
CAS No.	2253984-98-2
Molecular Formula	C28H48NOPS
Molecular Weight	477.72 g/mol
Synonyms	(S)-N-[(1S)-1-[2-(Dicyclohexylphosphanyl)phenyl]-2,2-dimethylpropyl]-2-methylpropane-2-sulfinamide; (S)-N-((S)-1-(2-(Dicyclohexylphosphino)phenyl)-2,2-dimethylpropyl)-2-methylpropane-2-sulfinamide; Sulfinamide-Phosphine Hybrid Ligand; Chiral Sulfinamide Phosphine Ligand; Asymmetric Catalysis Ligand; (S,S)-Sulfinamide Phosphine; CAS 2253984-98-2
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity, essential for reproducible catalytic performance. Each lot is characterized by comprehensive analytical techniques including NMR, HPLC, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess. We operate under a GMP-compliant quality management system to meet the exacting standards of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or ambient light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.