Description

1,3-Benzenedicarboxamide, N1,N3-Bis(2,3-Dihydroxypropyl)-5-[(2-Hydroxyethyl)Amino]-2,4,6-Triiodo- is a specialized, high-purity iodinated contrast agent intermediate designed for advanced pharmaceutical synthesis. This compound matters because it provides the essential triiodinated aromatic core required for developing next-generation, low-osmolality X-ray and CT imaging agents, ensuring superior diagnostic clarity and patient safety. It is critically needed by fine chemical manufacturers and R&D departments in the pharmaceutical industry focused on innovating non-ionic, water-soluble contrast media.

Application

• Key Intermediate for Non-Ionic Contrast Media: Primary building block for synthesizing modern iodinated contrast agents like Iopamidol, Iohexol, and Ioversol analogues.
• Pharmaceutical Research & Development (R&D): Used in the discovery and process development of new radiographic and computed tomography (CT) contrast agents.
• Fine Chemical Synthesis: Serves as a crucial precursor in multi-step organic synthesis for targeted molecule production.
• Diagnostic Imaging Agent Manufacturing: Integrated into GMP production lines for final active pharmaceutical ingredients (APIs) in contrast media.
• Chemical Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control testing.

Basic Information

Item	Details
Product Name	1,3-Benzenedicarboxamide, N1,N3-Bis(2,3-Dihydroxypropyl)-5-[(2-Hydroxyethyl)Amino]-2,4,6-Triiodo-
CAS No.	2253945-67-2
Molecular Formula	C16H22I3N3O6
Molecular Weight	Contact for details
Synonyms	5-[(2-Hydroxyethyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide; Triiodinated Isophthalamide Derivative; Non-Ionic Contrast Agent Intermediate; Iodinated Benzene-1,3-dicarboxamide; CT Contrast Media Intermediate; Iopamidol/Iohexol Intermediate; N1,N3-Bis(2,3-dihydroxypropyl)-5-(2-hydroxyethylamino)-2,4,6-triiodoisophthalamide
EINECS	Contact for details

Quality Control

Our 1,3-Benzenedicarboxamide, N1,N3-Bis(2,3-Dihydroxypropyl)-5-[(2-Hydroxyethyl)Amino]-2,4,6-Triiodo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting compliance with cGMP and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.