Description

Dexmedetomidine-018 is a high-purity pharmaceutical intermediate and reference standard, identified by CAS No. 2250243-56-0. This compound is critical for research and development in the synthesis of advanced sedative and analgesic agents. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories engaged in the development of central nervous system (CNS) therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of Dexmedetomidine and related α2-adrenergic receptor agonists.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing.
• Research & Development: Serves as a crucial material for preclinical studies and pharmacological research targeting sedation and analgesia.
• Process Chemistry: Utilized in route scouting and scale-up optimization for API (Active Pharmaceutical Ingredient) production.
• Impurity Profiling: Acts as a marker or related substance for impurity identification and control in final drug substance specifications.

Basic Information

Product Name	Dexmedetomidine-018
CAS No.	2250243-56-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dexmedetomidine Impurity 18; Dexmedetomidine Related Compound 18; Dexmedetomidine-018; Dexmedetomidine Derivative 18; Dexmedetomidine Analog 18; 2250243-56-0; Dexmedetomidine Process Intermediate
EINECS	Contact for details

Quality Control

Our Dexmedetomidine-018 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to support your regulatory and quality needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.