Description

S(R)]-n-[(R)-[2-(Diadamantanphosphino)Phenyl](2-Naphthalenyl)Methyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide ligand, distinguished by its unique diadamantylphosphino and naphthyl substituents. This compound matters as a highly effective and selective catalyst ligand for asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical for advanced pharmaceuticals. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in metal-catalyzed reactions.

Application

• Asymmetric Hydrogenation: As a chiral ligand for transition metals like rhodium and iridium in the enantioselective reduction of prochiral olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: For the production of chiral active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee), such as certain antiviral or cardiovascular drugs.
• Asymmetric C-C Bond Formation: Facilitating enantioselective cross-coupling, allylic alkylation, and conjugate addition reactions.
• Agrochemical Synthesis: In the development of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: As a key reagent for methodological development in organic synthesis and catalysis research.
• Fine Chemical Production: For manufacturing specialty chemicals, flavors, and fragrances where optical purity is paramount.

Basic Information

Product Name	S(R)]-n-[(R)-[2-(Diadamantanphosphino)Phenyl](2-Naphthalenyl)Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2249950-36-3
Molecular Formula	C40H47NOPS
Molecular Weight	605.83 g/mol
Synonyms	(R)-2-Methyl-2-propanesulfinamide, N-[[(R)-[2-(Diadamantan-1-ylphosphanyl)phenyl](naphthalen-2-yl)methyl]]-; (R)-N-[(R)-(2-(Bis(adamantan-1-yl)phosphino)phenyl)(naphthalen-2-yl)methyl]-2-methylpropane-2-sulfinamide; (R)-N-[(R)-(2-(Diadamantylphosphino)phenyl)(2-naphthyl)methyl]-tert-butanesulfinamide; Chiral Diadamantylphosphino-Sulfinamide Ligand; Sulfinamide-DAP Ligand; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our S(R)]-n-[(R)-[2-(Diadamantanphosphino)Phenyl](2-Naphthalenyl)Methyl]-2-Methyl-2-Propanesulfinamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assay, NMR for structural confirmation, and elemental analysis, to ensure it meets the high standards required for catalytic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and performance reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.