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3-Bromo-2-Fluoro-6-Methylphenylboronic Acid CAS NO 2246650-88-2


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CAS No.:2246650-88-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Bromo-2-Fluoro-6-Methylphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and the synthesis of novel chemical entities.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring halogenated, fluorinated aromatic scaffolds.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the bromo-fluoro-methyl substitution pattern can confer specific biological activity.
  • Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling polymerization.
  • Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
  • Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
  • Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CROs serving the global life sciences market.

Basic Information

Product Name 3-Bromo-2-Fluoro-6-Methylphenylboronic Acid
CAS No. 2246650-88-2
Molecular Formula C7H7BBrFO2
Molecular Weight 232.85 g/mol
Synonyms (3-Bromo-2-fluoro-6-methylphenyl)boronic acid; 2-Fluoro-6-methyl-3-bromophenylboronic acid; 3-Bromo-2-fluoro-6-methylbenzeneboronic acid; Boronic acid, B-(3-bromo-2-fluoro-6-methylphenyl)-; 2246650-88-2; 3-Br-2-F-6-MeC6H2B(OH)2
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Quality Control

Our 3-Bromo-2-Fluoro-6-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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