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3-Bromo-2-Fluoro-6-Methylphenylboronic Acid CAS NO 2246650-88-2
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CAS No.:2246650-88-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-2-Fluoro-6-Methylphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and the synthesis of novel chemical entities.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring halogenated, fluorinated aromatic scaffolds.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the bromo-fluoro-methyl substitution pattern can confer specific biological activity.
- Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling polymerization.
- Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
- Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
- Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CROs serving the global life sciences market.
Basic Information
| Product Name | 3-Bromo-2-Fluoro-6-Methylphenylboronic Acid |
| CAS No. | 2246650-88-2 |
| Molecular Formula | C7H7BBrFO2 |
| Molecular Weight | 232.85 g/mol |
| Synonyms | (3-Bromo-2-fluoro-6-methylphenyl)boronic acid; 2-Fluoro-6-methyl-3-bromophenylboronic acid; 3-Bromo-2-fluoro-6-methylbenzeneboronic acid; Boronic acid, B-(3-bromo-2-fluoro-6-methylphenyl)-; 2246650-88-2; 3-Br-2-F-6-MeC6H2B(OH)2 |
| EINECS | Contact for details |
Quality Control
Our 3-Bromo-2-Fluoro-6-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full analytical data are provided for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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