Description

5-Chloro-2,3-Difluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the precise construction of complex molecules for advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create biaryl structures in drug discovery and development.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Useful for constructing complex ligand frameworks in catalytic systems.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and probes for biological target identification.

Basic Information

Product Name	5-Chloro-2,3-Difluorophenylboronic Acid Pinacol Ester
CAS No.	2246586-13-8
Molecular Formula	C12H14BClF2O2
Molecular Weight	274.50 g/mol
Synonyms	5-Chloro-2,3-difluorophenylboronic acid pinacol ester; (5-Chloro-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(5-Chloro-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Chloro-2,3-difluorobenzeneboronic acid pinacol ester; Boronic acid, B-(5-chloro-2,3-difluorophenyl)-, 1,1-dimethylethyl ester; Pinacol (5-Chloro-2,3-difluorophenyl)boronate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Every batch is characterized by modern analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.