Description

3-Oxazolidinebutanenitrile, γ,2-Dioxo-4-(Phenylmethyl)-β-Propyl-, (βr,4S)- is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its complex oxazolidine-dione structure makes it a valuable precursor for constructing pharmacologically active molecules, particularly in the development of new therapeutic agents. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries who require sophisticated building blocks for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for generating compound libraries in high-throughput screening for new drug candidates.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional Research: Employed in universities and research institutes for studies in organic methodology development and chemical biology.

Basic Information

Item	Details
Product Name	3-Oxazolidinebutanenitrile, γ,2-Dioxo-4-(Phenylmethyl)-β-Propyl-, (βr,4S)-
CAS No.	2242963-07-9
Molecular Formula	C17H20N2O3
Molecular Weight	300.36 g/mol
Synonyms	(3R,4S)-γ,2-Dioxo-4-(phenylmethyl)-β-propyl-3-oxazolidinebutanenitrile; (3R,4S)-4-Benzyl-3-propyl-1,3-oxazolidine-2,5-dione propanenitrile derivative; 4-Benzyl-3-propyl-1,3-oxazolidine-2,5-dione-4-butanenitrile (stereoisomer); Chiral oxazolidinedione nitrile intermediate; CAS 2242963-07-9
EINECS	Contact for details

Quality Control

Every batch of 3-Oxazolidinebutanenitrile, γ,2-Dioxo-4-(Phenylmethyl)-β-Propyl-, (βr,4S)- is manufactured and tested under strict quality management systems. We ensure compliance with stringent internal specifications, which typically include identity confirmation, chiral purity (enantiomeric excess), and chemical purity assays. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.