Description

2-(1-Bicyclo[1.1.1]pentanyl)acetamide is a high-value, structurally constrained bicyclic acetamide derivative, identified by CAS NO 2242694-16-0. This compound is a critical pharmacophore and building block in modern medicinal chemistry, enabling the exploration of novel three-dimensional chemical space. It is primarily sought after by pharmaceutical R&D and agrochemical innovators for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation.
• Medicinal Chemistry Research: Used as a bioisostere for tert-butyl or phenyl groups to improve physicochemical properties like solubility and metabolic stability.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in linker design for creating novel targeted protein degraders.
• Agrochemical Synthesis: Intermediate in the research and development of new generation herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying protein function and biological pathways.
• Material Science Research: Potential monomer or additive for creating polymers with unique steric and electronic properties.

Basic Information

Item	Details
Product Name	2-(1-Bicyclo[1.1.1]pentanyl)acetamide
CAS No.	2242694-16-0
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	2-(Bicyclo[1.1.1]pentan-1-yl)acetamide; 1-Acetamidomethylbicyclo[1.1.1]pentane; [1.1.1]Propellane acetamide derivative; BCP-acetamide; Bicyclo[1.1.1]pentane-1-acetamide; (Bicyclo[1.1.1]pent-1-yl)acetamide; 2-(1-Bicyclo[1.1.1]pentyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-(1-Bicyclo[1.1.1]pentanyl)acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Custom synthesis and purification to meet specific research-grade or cGMP standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.