Description

(R)-n-((S)-1-Amino-1-Oxobutan-2-Yl)-3-(Bromomethyl)Hexanamide is a specialized chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting specific enzymatic pathways. Pharmaceutical researchers and fine chemical manufacturers need this high-purity intermediate for constructing complex peptidomimetics and other active pharmaceutical ingredients (APIs) where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, including protease inhibitors and other enzyme-targeted drugs.
• Peptidomimetic Synthesis: Used in constructing non-peptide compounds that mimic the structure and function of natural peptides for enhanced metabolic stability.
• Medicinal Chemistry Research: Serves as a versatile building block in structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation: The reactive bromomethyl group enables its use in linker chemistry for creating antibody-drug conjugates (ADCs) or other targeted delivery systems.
• Chemical Biology Probes: Utilized in the synthesis of activity-based probes for studying enzyme function and mechanism in biological systems.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.

Basic Information

Product Name	(R)-n-((S)-1-Amino-1-Oxobutan-2-Yl)-3-(Bromomethyl)Hexanamide
CAS No.	2242647-55-6
Molecular Formula	C11H21BrN2O2
Molecular Weight	293.20 g/mol
Synonyms	(R)-N-[(2S)-2-Aminobutanoyl]-3-(bromomethyl)hexanamide; 3-(Bromomethyl)-N-[(1S)-1-(aminocarbonyl)propyl]hexanamide, (3R)-; (3R)-3-(Bromomethyl)-N-[(2S)-2-aminobutanoyl]hexanamide; (R)-3-(Bromomethyl)-N-((S)-1-amino-1-oxobutan-2-yl)hexanamide; Bromomethyl Hexanamide Derivative; Chiral Bromoamide Intermediate; CAS 2242647-55-6
EINECS	Contact for details

Quality Control

Our (R)-n-((S)-1-Amino-1-Oxobutan-2-Yl)-3-(Bromomethyl)Hexanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.