Description

1-Propanol, 2-Amino-3-Fluoro-, Hydrochloride (1:1), (2R)- is a high-purity, single-enantiomer chiral building block essential for advanced pharmaceutical research and development. This compound provides a critical fluorinated amino alcohol scaffold for medicinal chemists, enabling the synthesis of novel drug candidates with enhanced metabolic stability and target selectivity. It is primarily utilized by R&D laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical industries for creating complex, bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Research: Used in the development of novel, fluorinated pesticides and herbicides, where the fluorine atom can improve lipophilicity and biological activity.
• Peptide Mimetics: Serves as a constrained, fluorinated amino acid analog in the design of peptide-based therapeutics and diagnostic agents.
• Ligand and Catalyst Development: Employed as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Useful for incorporating a stable fluorine label into molecules for studies using techniques like 19F NMR spectroscopy.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	1-Propanol, 2-Amino-3-Fluoro-, Hydrochloride (1:1), (2R)-
CAS No.	2242468-89-7
Molecular Formula	C3H9ClFNO
Molecular Weight	129.56 g/mol
Synonyms	(2R)-2-Amino-3-fluoropropan-1-ol hydrochloride; (R)-2-Amino-3-fluoropropyl alcohol hydrochloride; (R)-3-Fluoroalaninol hydrochloride; 3-Fluoro-D-alaninol hydrochloride; 2-Amino-3-fluoro-1-propanol hydrochloride, (2R)-; FA-ol hydrochloride; (R)-1-Amino-2-fluoro-3-hydroxypropane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Propanol, 2-Amino-3-Fluoro-, Hydrochloride (1:1), (2R)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.