Description

2-Pyridinemethanamine, n-[(1As,4As,9Bs)-10-[Bis[3,5-Bis(1,1-Dimethylethyl)Phenyl]Phosphino]-1A,2,3,4,4A,5-Hexahydro-1H-Indeno[2,1-D]Fluoren-9-Yl]-3-Methyl- is a sophisticated, sterically hindered phosphine ligand designed for advanced catalytic applications. Its molecular architecture, featuring a bulky indenofluorenyl backbone and a pyridinemethanamine substituent, provides exceptional stereoelectronic control in transition metal-catalyzed reactions. This high-value specialty chemical is essential for researchers and process chemists in pharmaceutical development and fine chemical synthesis who require precise selectivity and high activity.

Application

• Asymmetric Catalysis: A key ligand for enantioselective cross-coupling, hydrogenation, and hydrofunctionalization reactions in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Enables the construction of complex chiral molecules for active pharmaceutical ingredient (API) development.
• Fine Chemical Manufacturing: Used in the production of high-value agrochemicals, flavors, and fragrances where stereochemical purity is critical.
• Academic & Industrial Catalyst Discovery: Serves as a privileged scaffold for developing new catalytic systems in both academic and industrial R&D laboratories.
• Material Science: Potential applications in the synthesis of specialized polymers and advanced materials with tailored properties.

Basic Information

Product Name	2-Pyridinemethanamine, n-[(1As,4As,9Bs)-10-[Bis[3,5-Bis(1,1-Dimethylethyl)Phenyl]Phosphino]-1A,2,3,4,4A,5-Hexahydro-1H-Indeno[2,1-D]Fluoren-9-Yl]-3-Methyl-
CAS No.	2241655-67-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-[(1aS,4aS,9bS)-10-[Bis[3,5-di-tert-butylphenyl]phosphanyl]-1a,2,3,4,4a,5-hexahydro-1H-indeno[2,1-d]fluoren-9-yl]-3-methyl-2-pyridinemethanamine; Sterically Hindered Indenofluorenyl Phosphine Ligand; Asymmetric Phosphine Ligand; Chiral Phosphine Ligand; (S)-Indenofluorenyl Phosphine-Pyridinemethanamine Ligand; Specialty Catalytic Ligand 2241655-67-2
EINECS	Contact for details

Quality Control

Every batch of this high-purity ligand is manufactured and tested under strict quality control protocols to ensure consistency and performance. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and chiral integrity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.