Description

S(R)]-n-[(S)-[2-(Dicyclohexylphosphino)Phenyl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide is a high-value, chiral sulfinamide-phosphine hybrid ligand, a critical component in asymmetric synthesis. Its primary value lies in enabling highly enantioselective transition metal-catalyzed reactions, which are essential for producing single-enantiomer pharmaceuticals and fine chemicals. This advanced ligand is specifically designed for researchers and process chemists in pharmaceutical R&D, agrochemical development, and specialty chemical manufacturing who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation and transfer hydrogenation reactions.
• For enantioselective C-C bond formation in cross-coupling reactions (e.g., Suzuki-Miyaura, Heck).
• In the asymmetric synthesis of chiral amines and amino acid derivatives, key pharmaceutical intermediates.
• As a catalyst modifier for the production of single-enantiomer active pharmaceutical ingredients (APIs).
• For academic and industrial research in developing new catalytic methodologies.
• In the synthesis of complex natural products and other high-value specialty molecules.

Basic Information

Product Name	S(R)]-n-[(S)-[2-(Dicyclohexylphosphino)Phenyl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2241598-30-9
Molecular Formula	C₃₂H₄₂NOPS
Molecular Weight	519.72 g/mol
Synonyms	(S)-tert-Butanesulfinamide, N-[(1S)-1-[[2-(Dicyclohexylphosphino)phenyl](1-naphthyl)methyl]]-; (S)-N-[(S)-[2-(Dicyclohexylphosphino)phenyl](1-naphthyl)methyl]-2-methylpropane-2-sulfinamide; (S)-N-[(S)-[2-(Dicyclohexylphosphino)phenyl](1-naphthalenyl)methyl]-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; Dicyclohexylphosphino-based Sulfinamide Ligand; Asymmetric Hydrogenation Ligand; CAS 2241598-30-9
EINECS	Contact for details

Quality Control

Every batch of this advanced chiral ligand is produced and tested under strict quality control protocols to ensure consistency and performance in sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality system is designed to meet the rigorous demands of pharmaceutical development and research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. Due to its hygroscopic and easily oxidized nature, the container must be sealed immediately after use to minimize exposure to moisture and air. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.