Description

α-Capecitabine CAS NO 2230479-30-6 is a high-purity chemical intermediate, specifically a stereoisomer of the prodrug capecitabine, designed for advanced pharmaceutical research and development. Its precise molecular structure is critical for investigating structure-activity relationships and developing novel therapeutic agents. This compound is primarily targeted at research institutions and pharmaceutical companies engaged in oncology drug discovery, process chemistry, and analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis and research of novel antineoplastic (anti-cancer) agents.
• Research & Development: Used in academic and industrial laboratories for studying metabolic pathways, prodrug activation mechanisms, and isomer-specific biological activity.
• Process Chemistry: Employed in the development and optimization of synthetic routes for fluoropyrimidine-based pharmaceuticals.
• Analytical Standard: Acts as a high-purity reference standard for quality control, HPLC, LC-MS, and NMR analysis in pharmaceutical manufacturing.
• Preclinical Studies: Utilized in *in vitro* and *in vivo* studies to evaluate the efficacy and pharmacokinetics of specific capecitabine isomers.

Basic Information

Product Name	α-Capecitabine
CAS No.	2230479-30-6
Molecular Formula	C15H22FN3O6
Molecular Weight	359.35 g/mol
Synonyms	α-Capecitabine; (α)-Capecitabine; Capecitabine Isomer; 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine (α-isomer); N4-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine; Xeloda Isomer (α-form); Ro 09-1978/000 (Isomer); 5-Fluoro-1-(5-deoxy-β-D-ribofuranosyl)-2-oxo-1,2-dihydropyrimidine-4-carboxylic acid pentyl ester (α-configuration)
EINECS	Contact for details

Quality Control

Our α-Capecitabine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for isomeric composition, and spectroscopic identification (NMR, IR, MS). A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (α-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.