Description

3-(5-Bromo-6-Methyl-2-Pyridinyl)-2-Propyn-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine and propargyl alcohol functional groups. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers focused on developing targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Sonogashira couplings, due to the presence of the bromine and alkyne functionalities.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced functional materials.

Basic Information

Product Name	3-(5-Bromo-6-Methyl-2-Pyridinyl)-2-Propyn-1-Ol
CAS No.	2227448-95-3
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	5-Bromo-6-methyl-2-(2-propyn-1-ol)pyridine; 2-(Prop-2-yn-1-yloxy)-5-bromo-6-methylpyridine; 3-(5-Bromo-6-methylpyridin-2-yl)prop-2-yn-1-ol; (5-Bromo-6-methyl-2-pyridinyl)propargyl alcohol; Propargyl alcohol, 3-(5-bromo-6-methyl-2-pyridinyl)-; 5-Bromo-6-methyl-2-(prop-2-ynyloxy)pyridine
EINECS	Contact for details

Quality Control

Our 3-(5-Bromo-6-Methyl-2-Pyridinyl)-2-Propyn-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.