Description

2-Aminocyclopropane-1-Carbonitrile Hydrochloride is a high-value, specialized chemical building block featuring a strained cyclopropane ring system. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its unique structural motif, which can impart desirable biological activity and physicochemical properties to target molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the cyclopropane moiety can enhance potency and environmental profile.
• Chemical Biology Probe: Employed in the design and construction of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Peptidomimetics & Constrained Analogs: The rigid cyclopropane structure is valuable for creating conformationally restricted peptide analogs to improve metabolic stability and receptor selectivity.
• Material Science Research: Investigated as a monomer or cross-linking agent for the development of specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: A vital reagent for methodological development in organic chemistry, including studies on ring-opening reactions and asymmetric synthesis.

Basic Information

Product Name	2-Aminocyclopropane-1-Carbonitrile Hydrochloride
CAS No.	2227206-70-2
Molecular Formula	C4H7N2•HCl
Molecular Weight	134.58 g/mol
Synonyms	1-Cyano-1-cyclopropanamine hydrochloride; 1-Aminocyclopropanecarbonitrile hydrochloride; Cyclopropanecarbonitrile, 1-amino-, hydrochloride; 1-Cyclopropanamine-1-carbonitrile hydrochloride; ACC Hydrochloride; 2-Aminocyclopropanecarbonitrile HCl; 1-Amino-1-cyanocyclopropane hydrochloride; 1-Cyano-cyclopropylamine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Aminocyclopropane-1-Carbonitrile Hydrochloride is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.