Description

4-(Trifluoromethoxy)Cyclohexan-1-One is a high-value fluorinated organic building block characterized by its cyclohexanone core modified with a trifluoromethoxy substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in CNS and anti-inflammatory research.
• Agrochemical Synthesis: Used in creating advanced herbicides and pesticides where the trifluoromethoxy group enhances biological activity.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals with unique electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and as a scaffold for complex molecule construction in medicinal chemistry.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorinated alkoxy groups on chemical reactivity and physical properties.

Basic Information

Product Name	4-(Trifluoromethoxy)Cyclohexan-1-One
CAS No.	2227206-47-3
Molecular Formula	C7H9F3O2
Molecular Weight	182.14 g/mol
Synonyms	4-(Trifluoromethoxy)cyclohexanone; 4-(Trifluoromethoxy)cyclohexan-1-one; Cyclohexanone, 4-(trifluoromethoxy)-; 1-Cyclohexanone, 4-(trifluoromethoxy)-; 2227206-47-3; 4-Trifluoromethoxycyclohexanone; p-Trifluoromethoxycyclohexanone
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Cyclohexan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.