Description

3-Fluoro-2-Cyclopropylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its unique molecular architecture, combining a cyclopropyl group and a fluorine atom on the phenylboronic acid scaffold, which enables precise control over reaction pathways and final product properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for Suzuki-Miyaura cross-coupling reactions to create complex, functionalized biaryl structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide molecules, leveraging the metabolic stability imparted by the fluorine and cyclopropyl groups.
• Material Science Research: Serves as a monomer or linker in the development of advanced organic electronic materials, such as polymers for OLEDs and sensors.
• Ligand and Catalyst Development: Employed in the creation of novel palladium ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Fluoro-2-Cyclopropylphenylboronic Acid
CAS No.	2225178-10-7
Molecular Formula	C9H10BFO2
Molecular Weight	179.99 g/mol
Synonyms	(3-Fluoro-2-cyclopropylphenyl)boronic acid; 2-Cyclopropyl-3-fluorophenylboronic Acid; B-(3-Fluoro-2-cyclopropylphenyl)boronic Acid; 3-Fluoro-2-cyclopropylbenzeneboronic Acid; 2225178-10-7; Boronic acid, B-(3-fluoro-2-cyclopropylphenyl)-; AKOS026713293
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Cyclopropylphenylboronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry to verify identity, purity, and conformity to customer specifications. Our quality commitment ensures material traceability and supports regulatory filings in target industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.