Description

2-Fluoro-6-Chloropyridine-4-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique halogenated pyridine core with a boronic acid functional group makes it an indispensable reagent for constructing complex molecular architectures via cross-coupling reactions. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds and molecular probes used in diagnostic and biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-6-Chloropyridine-4-Boronic Acid
CAS No.	2225176-58-7
Molecular Formula	C5H4BClFNO2
Molecular Weight	175.36 g/mol
Synonyms	(6-Chloro-2-fluoropyridin-4-yl)boronic acid; 2-Fluoro-6-chloro-4-pyridineboronic acid; 4-Borono-2-fluoro-6-chloropyridine; 2-Fluoro-6-chloro-4-pyridinylboronic acid; 6-Chloro-2-fluoro-4-pyridineboronic acid; 2-Fluoro-6-chloro-4-boronopyridine; 4-Pyridineboronic acid, 6-chloro-2-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Chloropyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.