Description

5-Fluoro-2-(Morpholino)Pyridine-4-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its molecular structure, featuring both a morpholine ring and a boronic acid group, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine and morpholine motifs contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other advanced materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) agents due to its reactive boronic acid handle.
• Academic & Contract Research: A valuable reagent for methodology development and library synthesis in academic laboratories and contract research organizations (CROs).

Basic Information

Product Name	5-Fluoro-2-(Morpholino)Pyridine-4-Boronic Acid
CAS No.	2225174-90-1
Molecular Formula	C9H12BFN2O3
Molecular Weight	226.01 g/mol
Synonyms	5-Fluoro-2-morpholinopyridine-4-boronic acid; 4-Borono-5-fluoro-2-morpholinopyridine; 2-Morpholino-5-fluoropyridine-4-boronic acid; 5-Fluoro-2-(4-morpholinyl)-4-pyridineboronic acid; 4-Pyridineboronic acid, 5-fluoro-2-(4-morpholinyl)-; (5-Fluoro-2-morpholin-4-ylpyridin-4-yl)boronic acid; 2225174-90-1
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Morpholino)Pyridine-4-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.