Description

2-Fluoro-5-(tert-Butyl)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorine and tert-butyl groups confer desirable biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where its structure aids in tuning electronic properties.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Fluoro-5-(tert-Butyl)Phenylboronic Acid
CAS No.	2225155-59-7
Molecular Formula	C₁₀H₁₄BFO₂
Molecular Weight	196.03 g/mol
Synonyms	2-Fluoro-5-tert-butylbenzeneboronic acid; (2-Fluoro-5-tert-butylphenyl)boronic acid; 5-tert-Butyl-2-fluorophenylboronic acid; 2-Fluoro-5-(1,1-dimethylethyl)benzeneboronic acid; 2-Fluoro-5-(tert-butyl)phenylboronic acid pinacol ester (common derivative); 2-Fluoro-5-(tert-butyl)benzeneboronic acid; B-[2-Fluoro-5-(1,1-dimethylethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(tert-Butyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.