Description

2,6-Dimethyl-4-Trifluoromethylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing trifluoromethylated biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the stability of the pinacol ester for complex synthesis.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is paramount.
• Chemical Research: Acts as a versatile reagent in academic and industrial R&D for method development and exploring new chemical spaces.
• Ligand & Catalyst Development: Useful for constructing sophisticated ligand frameworks in catalysis due to its sterically hindered and electron-deficient aryl group.

Basic Information

Product Name	2,6-Dimethyl-4-Trifluoromethylphenylboronic Acid Pinacol Ester
CAS No.	2223051-36-1
Molecular Formula	C15H20BF3O2
Molecular Weight	300.13 g/mol
Synonyms	(4-(Trifluoromethyl)-2,6-dimethylphenyl)boronic acid pinacol ester; 2,6-Dimethyl-4-(trifluoromethyl)benzeneboronic acid pinacol ester; Pinacol [2,6-dimethyl-4-(trifluoromethyl)phenyl]boronate; 2,6-Dimethyl-α,α,α-trifluoro-p-tolylboronic acid pinacol ester; B-[2,6-Dimethyl-4-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[2,6-dimethyl-4-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-4-Trifluoromethylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.