Description

4-Bromo-5-Methyl-1H-Pyrazole-3-Carbonitrile is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the life sciences sector, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel active pharmaceutical ingredients (APIs), especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of new generation herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	4-Bromo-5-Methyl-1H-Pyrazole-3-Carbonitrile
CAS No.	2222511-91-1
Molecular Formula	C5H4BrN3
Molecular Weight	186.01 g/mol
Synonyms	4-Bromo-5-methyl-1H-pyrazole-3-carbonitrile; 5-Methyl-4-bromo-1H-pyrazole-3-carbonitrile; 3-Cyano-4-bromo-5-methyl-1H-pyrazole; 1H-Pyrazole-3-carbonitrile, 4-bromo-5-methyl-; 4-Bromo-5-methylpyrazole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Methyl-1H-Pyrazole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.