Description

Bb-Cl-Yne is a specialized alkyne-containing building block designed for advanced organic synthesis and pharmaceutical research. This high-purity intermediate is critical for constructing complex molecular architectures, particularly in medicinal chemistry and materials science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate unique halogenated alkyne functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs, enabling the introduction of alkyne groups for click chemistry or further functionalization.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where its specific halogen and alkyne motifs can contribute to biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the creation of specialty polymers, dendrimers, and functional materials with tailored properties.
• Chemical Biology & Bioconjugation: Employed in probe and linker synthesis for labeling biomolecules (proteins, nucleic acids) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Organic Synthesis Reagent: Acts as a versatile synthon in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Heck) to form carbon-carbon bonds.
• Ligand & Catalyst Development: Utilized for constructing novel ligand frameworks for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	Bb-Cl-Yne
CAS No.	2219324-71-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Bromo-3-chloro-5-ethynylbenzene (Tentative IUPAC based on name pattern); Bb-Cl-Alkyne; 3-Bromo-5-chlorophenylacetylene; Halogenated Aryl Alkyne; Building Block 2219324-71-5; Research Chemical 2219324-71-5; BCP Alkyne
EINECS	Contact for details

Quality Control

Our Bb-Cl-Yne is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.