Description

(2S,2'S,3S,3'S)-3,3'-Di-tert-Butyl-2,2'-Diisopropyl-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole is a high-purity, chiral organophosphorus compound with a complex, atropisomeric binaphthyl backbone. This compound matters as a sophisticated ligand precursor or catalyst in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a chiral ligand or catalyst in transition metal-catalyzed asymmetric reactions (e.g., hydrogenation, cross-coupling).
• As a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs).
• For research and development of asymmetric organocatalysis processes.
• In the synthesis of specialty polymers and advanced materials with specific chiral properties.
• As a reference standard or building block in academic and industrial chemistry research.
• Potential use in the development of chiral sensors or chromatographic stationary phases.

Basic Information

Product Name	(2S,2'S,3S,3'S)-3,3'-Di-tert-Butyl-2,2'-Diisopropyl-2,2',3,3'-Tetrahydro-4,4'-Bibenzo[D][1,3]Oxaphosphole
CAS No.	2207601-12-3
Molecular Formula	C34H44O2P2
Molecular Weight	546.64 g/mol
Synonyms	BIBOP Derivative; Chiral Binaphthyl Phosphole; (S,S)-3,3'-Di-tert-butyl-2,2'-diisopropyl-2,2',3,3'-tetrahydro-4,4'-bibenzo[d][1,3]oxaphosphole; Atropisomeric Dihydrooxaphosphole Ligand; BIBOP-*tBu,*iPr; Tetrahydro-4,4'-bibenzo[d][1,3]oxaphosphole derivative; CAS 2207601-12-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing specific results for each lot are available upon request. We adhere to a cGMP-compliant quality management system suitable for supporting pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.