Description

Ticagrelor Related Compound CAS NO 2205903-74-6 is a high-purity chemical reference standard used in the pharmaceutical development and quality control processes for the antiplatelet drug Ticagrelor. This compound is critical for ensuring the safety, efficacy, and regulatory compliance of the final drug product by serving as a benchmark for impurity identification and quantification. It is an essential material for analytical laboratories, pharmaceutical manufacturers, and research institutions focused on cardiovascular therapeutics.

Application

• Pharmaceutical Impurity Profiling: Used as a certified reference material (CRM) for the identification and quantification of specific impurities in Ticagrelor active pharmaceutical ingredient (API) and finished dosage forms.
• Analytical Method Development and Validation: Serves as a critical standard for developing, calibrating, and validating High-Performance Liquid Chromatography (HPLC) and other chromatographic methods.
• Quality Control (QC) and Quality Assurance (QA): Employed in routine batch release testing to ensure Ticagrelor products meet stringent pharmacopeial standards (e.g., USP, EP) for purity and impurity limits.
• Stability Studies: Acts as a marker compound in forced degradation and long-term stability studies to monitor the formation of related substances over time.
• Regulatory Submissions: Provides essential data for regulatory filings (e.g., with FDA, EMA) to demonstrate comprehensive control of the drug substance's impurity profile.
• Research and Development: Utilized in synthetic chemistry research to study the degradation pathways and metabolism of Ticagrelor.

Basic Information

Item	Details
Product Name	Ticagrelor Related Compound
CAS No.	2205903-74-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ticagrelor Impurity; Ticagrelor Related Substance; Ticagrelor Degradation Product; Ticagrelor Process Impurity; (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol (possible isomer/structure); AZD6140 Related Compound; AR-C126532XX Related Substance
EINECS	Contact for details

Quality Control

Every batch of our Ticagrelor Related Compound is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with ICH Q3A/B guidelines for impurities and relevant pharmacopeial standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by validated methods (HPLC, MS, NMR).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 0.5% Total impurities: ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.