Description

1-(2-Bromo-4-Trifluoromethylphenyl)-Ethylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its bromine and trifluoromethyl substituents on the aromatic ring. This compound is crucial for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those requiring halogenated and fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bromine and trifluoromethyl groups can contribute to biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and target engagement.
• Custom Synthesis: An essential starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and process development.

Basic Information

Product Name	1-(2-Bromo-4-Trifluoromethylphenyl)-Ethylamine Hydrochloride
CAS No.	2204562-89-8
Molecular Formula	C9H8BrClF3N
Molecular Weight	302.52 g/mol
Synonyms	1-(2-Bromo-4-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride; α-Methyl-2-bromo-4-(trifluoromethyl)benzylamine hydrochloride; 2-Bromo-α-methyl-4-(trifluoromethyl)benzenemethanamine hydrochloride; 1-(2-Bromo-4-trifluoromethyl-phenyl)-ethylamine HCl; (1-(2-Bromo-4-(trifluoromethyl)phenyl)ethyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Trifluoromethylphenyl)-Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.