Description

4-Cyano-2,6-Difluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in serving as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the difluoro and cyano substituents for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED emitters and charge transport materials, where the molecular structure influences optoelectronic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for studying biological processes, taking advantage of its boronic acid functionality for selective binding.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Cyano-2,6-Difluorophenylboronic Acid
CAS No.	2199440-52-1
Molecular Formula	C7H4BF2NO2
Molecular Weight	182.93 g/mol
Synonyms	(4-Cyano-2,6-difluorophenyl)boronic Acid; 2,6-Difluoro-4-cyanophenylboronic Acid; 4-Cyano-2,6-difluorobenzeneboronic Acid; B-(4-Cyano-2,6-difluorophenyl)boronic Acid; 2199440-52-1; 4-CN-2,6-F2-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 4-Cyano-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.