Description

tert-Butyl 4-[2-Cyano-3-(Dimethylamino)Prop-2-Enoyl]Piperazine-1-Carboxylate is a sophisticated piperazine-based building block featuring a cyanoenone functional group. This compound is of significant value in pharmaceutical research and development as a key intermediate for constructing complex molecules. It is primarily utilized by medicinal chemists and process development scientists in the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce specific pharmacophores.
• Process Chemistry Development: Serves as a key starting material for scaling up the production of advanced intermediates under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the bespoke synthesis of proprietary compounds for clients.
• Chemical Biology Probes: Can be utilized to create tool compounds for studying enzyme mechanisms or protein-ligand interactions.

Basic Information

Product Name	tert-Butyl 4-[2-Cyano-3-(Dimethylamino)Prop-2-Enoyl]Piperazine-1-Carboxylate
CAS No.	2197064-33-6
Molecular Formula	C15H22N4O3
Molecular Weight	306.36 g/mol
Synonyms	1-Boc-4-(2-cyano-3-(dimethylamino)acryloyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(2-cyano-3-(dimethylamino)acryloyl)piperazine; tert-Butyl 4-(2-cyano-3-(dimethylamino)acryloyl)piperazine-1-carboxylate; 4-[2-Cyano-3-(dimethylamino)prop-2-enoyl]piperazine-1-carboxylic acid tert-butyl ester; Boc-Piperazine-Cyanoenone; (E)-tert-Butyl 4-(2-cyano-3-(dimethylamino)acryloyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[2-Cyano-3-(Dimethylamino)Prop-2-Enoyl]Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.