Description

Azido-Peg23-Amine is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive azide group and a primary amine group, separated by a 23-unit PEG spacer. This compound is a critical building block in bioconjugation and materials science, enabling the creation of stable, well-defined linkages between diverse molecules and surfaces under mild conditions. It is essential for researchers and manufacturers in pharmaceutical development, advanced material synthesis, and diagnostic assay production who require precise, water-soluble, and biocompatible crosslinking agents.

Application

• Bioconjugation and ADC Development: Used for site-specific conjugation of antibodies, proteins, or peptides to drugs, toxins, or fluorophores via click chemistry (e.g., with DBCO or alkyne-functionalized molecules).
• PEGylation and Linker Chemistry: Serves as a heterobifunctional linker to introduce PEG chains onto surfaces or biomolecules, improving solubility, stability, and pharmacokinetics.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, or solid supports (e.g., glass, gold) with amine-reactive groups for subsequent biomolecule immobilization.
• Hydrogel and Polymer Synthesis: Acts as a crosslinker or functional monomer in the creation of smart hydrogels and biocompatible polymers for drug delivery and tissue engineering.
• Diagnostic Reagent Preparation: Utilized to label oligonucleotides, antibodies, or other probes for use in fluorescence in situ hybridization (FISH), ELISA, or lateral flow assays.
• Materials Science Research: Applied in the development of self-assembled monolayers (SAMs) and functional coatings with tailored surface properties.

Basic Information

Item	Detail
Product Name	Azido-Peg23-Amine
CAS No.	2172677-19-7
Molecular Formula	C47H96N4O23
Molecular Weight	~1109.3 g/mol
Synonyms	Azido-PEG23-amine; N3-PEG23-NH2; α-Azido-ω-amino-triethylene glycol; 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68-Heneicosaoxa-71-azaoctaheptacont-73-yn-75-amine; Azido-PEG-NH2 (n=23); PEG23 azide amine; Heterobifunctional PEG Azide Amine (MW 1100)
EINECS	Contact for details

Quality Control

Our Azido-Peg23-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and functional group integrity, NMR for structural confirmation, and mass spectrometry for molecular weight verification. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Amine Value	Contact for details
Azide Content	Contact for details
Molecular Weight (MS)	1109.3 ± 5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.