Description

Bromoacetamido-Peg11-Azido is a heterobifunctional polyethylene glycol (PEG) linker featuring a bromoacetamide group and an azide terminus. This compound is specifically engineered for the site-specific conjugation of biomolecules, enabling the creation of stable, well-defined constructs. It is an essential reagent for researchers and developers in the fields of bioconjugation, ADC (Antibody-Drug Conjugate) development, and advanced material science, where precise and controlled coupling is required. The product is supplied with CAS No. 2172677-17-5.

Application

• Bioconjugation and ADC Development: Site-specific modification of antibodies, proteins, and peptides via the reactive bromoacetamide group, which selectively targets cysteine residues.
• Click Chemistry: Facile conjugation of azide-functionalized molecules (e.g., dyes, drugs, polymers) to alkyne-bearing targets via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• PEGylation: Introduction of a long, hydrophilic PEG11 spacer to improve solubility, stability, and pharmacokinetic properties of therapeutic agents.
• Polymer and Material Science: Building block for synthesizing functionalized hydrogels, smart materials, and surface coatings with tailored bio-interfaces.
• Diagnostic Probe Synthesis: Creation of imaging probes and biosensors by conjugating targeting molecules with reporter groups.
• Drug Delivery Systems: Fabrication of targeted nanocarriers and liposomes for controlled drug release.

Basic Information

Product Name	Bromoacetamido-Peg11-Azido
CAS No.	2172677-17-5
Molecular Formula	C31H59BrN4O13
Molecular Weight	~775.71 g/mol
Synonyms	Azido-PEG11-Bromoacetamide; Bromoacetamido-PEG11-N3; N3-PEG11-Bromoacetamide; 2-Bromo-N-(2,5,8,11,14,17,20,23,26,29,32-undecaoxa-34-azapentatriacontan-35-yl)acetamide; Heterobifunctional PEG Linker, Bromoacetamide-Azide; Bromoacetyl-PEG11-Azide; Azido-Polyethylene Glycol-Bromoacetamide (MW ~500); Bromoacetamide-PEG-Azide (n=11)
EINECS	Contact for details

Quality Control

Our Bromoacetamido-Peg11-Azido is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for critical research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional group integrity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Assay (Azide)	≥ 90%
Functional Group Assay (Bromoacetamide)	≥ 90%
Solubility	Soluble in DMSO, DMF, water, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.