Description

(1-Isopropyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)Boronic Acid is a high-value, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by pharmaceutical and agrochemical R&D teams for the discovery and development of new active ingredients, where the pyrazole and trifluoromethyl motifs are highly sought-after for their biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in synthesizing novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the pyrazole and trifluoromethyl groups.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) companies producing bespoke compounds for client projects.
• Academic & Industrial R&D: Fundamental research reagent in universities and corporate labs for methodology development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	(1-Isopropyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)Boronic Acid
CAS No.	2170881-31-7
Molecular Formula	C8H12BF3N2O2
Molecular Weight	236.00 g/mol
Synonyms	1-Isopropyl-3-(trifluoromethyl)-1H-pyrazole-4-boronic acid; 4-Borono-1-isopropyl-3-(trifluoromethyl)-1H-pyrazole; (1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid; 1H-Pyrazole-4-boronic acid, 1-(1-methylethyl)-3-(trifluoromethyl)-; B-[1-Isopropyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our (1-Isopropyl-3-(Trifluoromethyl)-1H-Pyrazol-4-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and potentially air-sensitive nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.