Description

(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-5-Hydroxypentanoic Acid is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound matters as a critical building block for the controlled assembly of complex peptides and peptidomimetics in pharmaceutical research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic agents and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the sequential construction of peptides on resin.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based drugs, including hormones, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or surfaces.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Peptidomimetic Design: Provides a scaffold for creating modified peptides with enhanced stability, bioavailability, or activity.
• Academic & Industrial R&D: Fundamental reagent for studying protein-protein interactions, signal transduction, and metabolic pathways.

Basic Information

Product Name	(2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-5-Hydroxypentanoic Acid
CAS No.	2169956-19-6
Molecular Formula	C20H21NO5
Molecular Weight	355.39 g/mol
Synonyms	Fmoc-5-hydroxy-L-norvaline; Fmoc-L-Hon-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-hydroxy-L-norvaline; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-5-hydroxypentanoic acid; Fmoc-5-hydroxy-L-norvaline-OH; Nα-Fmoc-5-hydroxy-L-norvaline; 5-Hydroxy-L-norvaline, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our (2S)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}Amino)-5-Hydroxypentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting research and pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.