Description

(2S,2'S,3S,3'S)-3,3'-Di-tert-Butyl-4,4'-Bis((S)-2-Methyl-1-Phenylpropoxy)-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole is a sophisticated chiral organophosphorus compound, specifically a binaphthol-derived phosphite ligand, valued for its role in asymmetric synthesis. Its primary commercial value lies in its application as a highly effective ligand for transition metal catalysts, enabling enantioselective transformations critical for producing high-value intermediates. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for rhodium, iridium, or palladium catalysts in enantioselective hydrogenation, hydroformylation, and C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: For the production of single-enantiomer active pharmaceutical ingredients (APIs) where high optical purity is mandated.
• Agrochemical Manufacturing: In the synthesis of chiral herbicides, fungicides, and pesticides to enhance efficacy and reduce environmental impact.
• Advanced Material Research: As a building block or chiral auxiliary in the development of novel polymers and functional materials with specific optical properties.
• Academic & Industrial R&D: For method development and exploration of new catalytic systems in organic and organometallic chemistry laboratories.

Basic Information

Product Name	(2S,2'S,3S,3'S)-3,3'-Di-tert-Butyl-4,4'-Bis((S)-2-Methyl-1-Phenylpropoxy)-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole
CAS No.	2169292-11-7
Molecular Formula	C52H64O4P2
Molecular Weight	814.99 g/mol
Synonyms	(S,S)-DTB-BINAPO; (S,S)-3,3'-Di-tert-butyl-2,2'-bis((S)-2-methyl-1-phenylpropoxy)-2,2',3,3'-tetrahydro-4,4'-bi-1,3-benzoxaphosphole; Chiral Binaphthol Phosphite Ligand; (S,S)-DTB-Binaphthoxaphosphole; (S,S)-DTB-BOP; (S,S)-3,3'-Di-t-butyl-4,4'-bis((S)-2-methyl-1-phenylpropoxy)-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole
EINECS	Contact for details

Quality Control

Our production of this high-purity chiral ligand adheres to stringent quality protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR (¹H and ³¹P), and chiral analysis to confirm identity, chemical purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, cool place. Due to its hygroscopic and easily oxidized nature, containers must be sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.