Description

D-β-Holys(Boc)-Oh is a high-purity, protected amino acid derivative, widely recognized under the CAS number 2165435-43-6. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly in the production of complex peptides and active pharmaceutical ingredients (APIs). It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies requiring precise stereochemistry and reliable quality for their processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and novel therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of specific amino acid residues.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amine functionalities in multi-step synthetic routes.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other bioconjugate platforms.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies.
• Custom Synthesis: Serves as a starting material for the custom manufacturing of specialized fine chemicals and reference standards.

Basic Information

Product Name	D-β-Holys(Boc)-Oh
CAS No.	2165435-43-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	D-β-Homolysine(Boc)-OH; (R)-2-((tert-Butoxycarbonyl)amino)-6-aminohexanoic acid (Boc-D-β-Lys-OH); Boc-D-β-Lysine; Nα-Boc-D-β-lysine; D-β-Lys(Boc); Nα-(tert-Butoxycarbonyl)-D-β-lysine; D-2-Amino-6-((tert-butoxycarbonyl)amino)hexanoic acid
EINECS	Contact for details

Quality Control

Our D-β-Holys(Boc)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests to ensure compliance with high-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.