Description

[S(R)]-n-[(1R)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide is a high-value, chiral sulfinamide ligand derivative, specifically designed for asymmetric synthesis and catalysis. Its core value lies in its ability to act as a highly selective and efficient ligand for transition metal-catalyzed reactions, enabling the production of enantiomerically pure compounds critical for advanced research and development. This compound is essential for pharmaceutical chemists, process R&D scientists, and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for transition metals like palladium, rhodium, and iridium in cross-coupling, hydrogenation, and hydroformylation reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the stereoselective construction of complex molecular architectures for novel drug candidates and APIs.
• Methodology Development: Serving as a key reagent in academic and industrial research for developing new catalytic asymmetric transformations.
• Fine Chemical Production: Used in the manufacture of enantiomerically pure flavors, fragrances, and advanced materials.
• Agrochemical Research: Facilitating the synthesis of chiral active ingredients with improved efficacy and environmental profiles.

Basic Information

Item	Details
Product Name	[S(R)]-n-[(1R)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2162939-92-4
Molecular Formula	C38H44NO2PS
Molecular Weight	609.80 g/mol
Synonyms	(SR)-N-[(1R)-1-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]-2,2-dimethylpropyl]-2-methylpropane-2-sulfinamide; Xantphos-Derived Chiral Sulfinamide Ligand; Chiral Sulfinamide-PPh3 Hybrid Ligand; (R)-DTBM-SEGPHOS Sulfinamide Analog; Asymmetric Sulfinamide Ligand CAS 2162939-92-4
EINECS	Contact for details

Quality Control

Every batch of [S(R)]-n-[(1R)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet the stringent requirements for catalytic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.