Description

[S(R)]-n-[(S)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Ethyl]-2-Methyl-2-Propanesulfinamide CAS NO 2162939-90-2 is a sophisticated chiral sulfinamide ligand, characterized by its xanthene backbone and diphenylphosphino group, designed for high-precision asymmetric synthesis. This compound is a critical component for enabling highly enantioselective transformations, offering researchers and process chemists a powerful tool to control stereochemistry in complex molecule construction. It is primarily utilized by the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and addition reactions.
• For the enantioselective synthesis of pharmaceutical intermediates and active ingredients requiring high optical purity.
• In academic and industrial R&D for developing novel catalytic methodologies and exploring new chemical space.
• As a key reagent in the preparation of complex natural products and specialty chemicals where stereocontrol is paramount.
• For process development and scale-up in GMP-compliant manufacturing environments for pharmaceutical production.

Basic Information

Product Name	[S(R)]-n-[(S)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]Ethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2162939-90-2
Molecular Formula	C33H36NO2PS
Molecular Weight	541.70 g/mol
Synonyms	(S)-tert-Butanesulfinamide, (S)-DTBM-SEGPHOS derivative; Chiral Xantphos Sulfinamide Ligand; (SR)-N-[(1S)-1-[5-(Diphenylphosphanyl)-9,9-dimethyl-9H-xanthen-4-yl]ethyl]-2-methylpropane-2-sulfinamide; Asymmetric Sulfinamide Ligand; SPhos-type Sulfinamide; (S)-DTBM-SEGPHOS-Sulfinamide; tert-Butylsulfinyl Imine Precursor Ligand
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by comprehensive analytical techniques including HPLC, NMR, and chiral analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and chiral integrity to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged manipulations to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.