Description

[S(R)]-n-[(1S)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral ligand and organocatalyst, specifically designed for asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer pharmaceuticals and fine chemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including cross-couplings and hydrogenations.
• Pharmaceutical Intermediate Synthesis: For the enantioselective construction of complex molecular scaffolds in active pharmaceutical ingredient (API) development.
• Organocatalysis: Acting as a catalyst in enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Methodology Development: A key reagent for academic and industrial research into new synthetic methodologies.
• Agrochemical Research: Used in the synthesis of chiral active ingredients for crop protection agents.
• Material Science: Potential applications in the synthesis of chiral polymers or liquid crystals.

Basic Information

Product Name	[S(R)]-n-[(1S)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide
CAS No.	2162939-89-9
Molecular Formula	C38H44NO2PS
Molecular Weight	609.80 g/mol
Synonyms	(SR)-N-[(1S)-1-[5-(Diphenylphosphino)-9,9-dimethyl-9H-xanthen-4-yl]-2,2-dimethylpropyl]-2-methylpropane-2-sulfinamide; Xantphos-Derived Chiral Sulfinamide Ligand; Chiral Xantphos Sulfinamide; (S)-DTBM-SEGPHOS-Type Sulfinamide Ligand; Asymmetric Sulfinamide Ligand CAS 2162939-89-9; SPhos Sulfinamide Derivative; Chiral Phosphine-Sulfinamide Hybrid Ligand
EINECS	Contact for details

Quality Control

Our [S(R)]-n-[(1S)-1-[5-(Diphenylphosphino)-9,9-Dimethyl-9H-Xanthen-4-Yl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to prevent oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.